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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DKC1 All Species: 54.55
Human Site: S102 Identified Species: 85.71
UniProt: O60832 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60832 NP_001354.1 514 57674 S102 D K P S N P S S H E V V A W I
Chimpanzee Pan troglodytes XP_521345 595 65925 S183 D K P S N P S S H E V V A W I
Rhesus Macaque Macaca mulatta XP_001090867 597 66468 S185 D K P S N P S S H E V V A W I
Dog Lupus familis XP_549382 517 57997 S102 D K P S N P S S H E V V A W I
Cat Felis silvestris
Mouse Mus musculus Q9ESX5 509 57483 S102 D K P S N P S S H E V V A W I
Rat Rattus norvegicus P40615 509 56597 S103 D K P S N P S S H E V V A W I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514686 519 58453 S104 D K P S N P S S H E V V A W I
Chicken Gallus gallus Q5ZJH9 516 58132 S100 D K P S N P S S H E V V A W I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028279 506 56658 S97 D K P A N P S S H E V V A W I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O44081 508 56812 S100 D K P S N P S S H E V V A W I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17919 445 50192 G63 H Y T P H V E G V S P L K R D
Sea Urchin Strong. purpuratus XP_001187533 541 60439 S95 D K P A N P S S H E V V S W V
Poplar Tree Populus trichocarpa XP_002323264 482 54054 S89 D K P A N P S S H E V V A W I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LD90 565 63008 S93 D K P A N P S S H E V V A W I
Baker's Yeast Sacchar. cerevisiae P33322 483 54686 K87 K R I L R C E K T G H S G T L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 85.5 89.9 N.A. 90 83.2 N.A. 85.3 81.4 N.A. 74.7 N.A. 64.7 N.A. 58.7 64.8
Protein Similarity: 100 85.3 86 93.6 N.A. 93.1 90.8 N.A. 88.8 89.9 N.A. 85.4 N.A. 77.6 N.A. 71.4 77
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 N.A. 100 N.A. 0 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 100 N.A. 13.3 100
Percent
Protein Identity: 61.2 N.A. N.A. 57.5 57.9 N.A.
Protein Similarity: 76.4 N.A. N.A. 73.4 71.9 N.A.
P-Site Identity: 93.3 N.A. N.A. 93.3 0 N.A.
P-Site Similarity: 100 N.A. N.A. 100 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 27 0 0 0 0 0 0 0 0 80 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 87 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % D
% Glu: 0 0 0 0 0 0 14 0 0 87 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 7 0 7 0 0 7 0 0 % G
% His: 7 0 0 0 7 0 0 0 87 0 7 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 80 % I
% Lys: 7 87 0 0 0 0 0 7 0 0 0 0 7 0 0 % K
% Leu: 0 0 0 7 0 0 0 0 0 0 0 7 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 87 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 87 7 0 87 0 0 0 0 7 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 0 0 7 0 0 0 0 0 0 0 0 7 0 % R
% Ser: 0 0 0 60 0 0 87 87 0 7 0 7 7 0 0 % S
% Thr: 0 0 7 0 0 0 0 0 7 0 0 0 0 7 0 % T
% Val: 0 0 0 0 0 7 0 0 7 0 87 87 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 87 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _